Trinity is developing a broad pipeline of vaccine candidates in major
areas of unmet medical need. In particular, it is focused on respiratory,
digestive and sexually transmitted diseases — areas that would
benefit greatly from enhanced mucosal protection. Its pipeline includes
vaccines against the following pathogens:
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Pseudomonas
aeruginosa; one of the most ubiquitous infectious agents in our
everyday environment. It colonizes the lungs of essentially all
CF patients and is one of the most common infections in AIDS patients,
as well as burn and trauma victims.
Chlamydia trachomatis;
the most common sexually transmitted disease in the US. Even when
the symptoms of disease are not apparent, this pathogen is
responsible for infertility and other complications in up to 25% of the people
it infects.
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An effective vaccine against these infectious agents would provide very
significant patient benefit and represent major cost savings to the healthcare
system.
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